Cobalamin, methylmalonic acid (MMA), and homocysteine are interconnected metabolically. Elevated MMA and/or homocysteine levels in the blood can indicate a functional deficiency of cobalamin, even when serum cobalamin levels appear within the... Read more »
Methylmalonic acid (MMA) and homocysteine are metabolic intermediates. Elevated concentrations of these substances in the blood often indicate a disruption in specific metabolic pathways. One common cause of such disruption is vitamin... Read more »
Elevated levels of both homocysteine and methylmalonic acid (MMA) are common metabolic indicators of vitamin B12 deficiency. Homocysteine, an amino acid, requires B12 for its conversion back to methionine. MMA, a byproduct... Read more »
Methylmalonic acid (MMA) and homocysteine are metabolites whose levels in the blood can help differentiate between vitamin B12 and folate deficiencies. Both deficiencies can lead to elevated homocysteine, while only a B12... Read more »
Methylmalonic acid (MMA), homocysteine, and vitamin B12 are interconnected biomarkers often evaluated together to assess vitamin B12 status. Elevated MMA levels, coupled with elevated homocysteine and/or low vitamin B12 levels, can suggest... Read more »